Question 1: The advantage of nc3 is that it is the best square for the knight, and influences the center. However, it blocks the c-pawn and can be pinned by Bb4.
Nd2 is more flexible, as the knight can go to f3 if the other knight goes to e2. Seems a little strange at first, but I've seen it done. Also, no pins, as the c-pawn can intervene. The downside of Nd2 is that it blocks the c-bishop, and does not directly influence the center. However, a pawn on c3 helps solidify the center.
Question 2: 1. e3 is not very popular in GM play or at the club level, but I'm sure some will use it. It tends to steer the game towards reversed French (1. e3 e5 2. d4), reversed Nimzo-Indian, the Nimzo-Larsen attack (1. e3 d5 2. Nf3 c5 3. b3), or some form of the flexible Reti Opening if black does not play 1. ...e5.
Something to try, I suppose. Probably not reliable enough to be a main opening as White, but definitely lower on theory than more mainstream openings like e4 or d4.