Well, Larsen's 2. b3 is not a route to an opening advantage, but if that is o.k. with you it is a perfectly reasonable move. If you are open to playing 3. d4 though, I question whether you shouldn't be playing 2. d4 (or 1. d4!), since the point of 2. b3 is to secure the long diagonal for the dark squared bishop.
After 1. Nf3 d6 2. b3 e5, I would play 3. c4, and follow up with Nc3, g3, and Bg2 before considering a central advance.
It's more likely to give you an advantage to transpose to something more normal, like 2. d4 Nf6 3. c4.