I ignore the sicilian altogether and play 1.Nf3!

But e4 is perfectly good. However the open sicilian is really tough to deal with if black knows what to do. The Smith-Morra gambit has a pretty easy plan to follow and is active for white and not so much for black. You would have to deal with the anti smith morras though. As previously stated in this post the Alapin is a safe and straightforward way to combat the sicilian. It's your choice.