There is a way (I think) to delete one's own
thread. Not to worry, there's usually a Perseus uhm, I mean a
moderator around to help with that

. This time I physically removed the double, instead of leaving the thread title in the list with the note that it's deleted. As I don't think there's a need for the double to be around, I'll keep doing that for now..
What I gather is you want a system for white and black that is immune to all replies. Hmm.. as you may know, you'll have to compromise a bit because chess isn't simple.. at any rate.
You're a positional player with a d4/french/nimzo background. That's not a bad way to play.
Black
There's an "all-purpose defense" that works against (just about) any opening known to mankind. The most commonly seen opening in it is the Tarrasch QGD. The pawns are set up in a chain with c5-d5-e6 (not necessarily in that order of course), then there is Nf6, Nc6, Bd6, all very natural chess. It plays just like a French, but there are move order differences when white hasn't played 1. e4.
Which why I would never play 1. e4 e6 2. d4 d5 3. Nc3 c5 as black, because white gets to put black in an awkward spot, which isn't quite as possible in the non-1.e4 territory.
I used to pick a defense against 1. e4 and pick a defense for everything else. For a long time I played a Dutch formation everytime my opponent had the audacity to play moves like d4, c4, Nf3, Nc3, d3, e3, b3, g3 (or whatever!) on move 1. I had good results because I knew my setup well enough to fit my opponent's position into my plans.
I briefly tried various Slav lines following 1. d4 c6. I did that after reading various articles on the similarities between the Slav and the Caro-Kann (which I like). I found out the Slav isn't my cup of tea and I ended up transposing into various QGD lines (I think). I played some decent defensive chess though.
White
Well, the Colle is simple. Basically it's a QGD (/Slav-ish) with colours reversed. The moves are natural and you won't get in trouble. You'll get nothing out of the opening except maybe an advantage the size of a pixel, but that isn't where the Colle excels. The Colle depends on you being comfortable with it. If you know your system through and through and your opponent doesn't spend much time on the thing (it isn't
that dangerous for black) your practical chances are better than theory suggests. Also, if you're generally a skilled player in middle games, making all sorts of attacks out of a
nice position the Colle might work for you.
If the Exchange French disturbs you, don't play the French in the first place. There are a plethora of ways for black to gradually outplay white even if white is playing decent chess (I've found that out myself). Keep in mind white plays the Exchange to annoy you, if he succeeds in that, you've pretty much failed

.
The Exchange line in the QGD:
1. d4 d5 2. c4 e6 3. cxd5 exd5
Now compare that to this, the Exchange variation of the Caro-Kann:
Noticed something? Same position, reversed colours. Unfortunately, you don't get the usual extra tempo because of the moves not being vertically symmetrical but that doesn't matter. In the QGD line you'll have the open position white has in the CKD line which in my opinion results in equality.
For what it's worth, here's my €0,02